C14orf93 is a protein that is encoded in humans by the C14orf93 gene. C14orf93 (also named as Regulator of Thyroid Function and Cancer, RTFC) as a novel susceptibility gene for familial nonmedullary thyroid cancer. It is a globular protein with a conserved C-terminus that is localized to the nucleus. While expressed relatively highly in all tissues except nervous tissue, it is expressed particularly highly in T cells and other immune tissues. c14orf93 is expressed 2.7 times higher than the average gene across all tissues. It is expressed relatively highly in all tissues except for nervous tissue. There is markedly higher expression seen in T cells, and there is a slightly higher expression pattern shown in other immune tissues such as bone marrow, spleen, and lymph nodes.