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  3. CD79a Recombinant Rabbit Monoclonal Antibody [JE32-14]
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CD79a Recombinant Rabbit Monoclonal Antibody [JE32-14]

Product ID: 402147863651


Gentaur Catalog Number

GTR09940371
Select size

100 µL

$726.85
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Selected
100 µL

$726.85

1

Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.