Detergents have been shown to aid in the protein refolding process both of native and recombinant proteins. Detergents are usually used as a step in the protein refolding process often in conjunction with cyclodextrins. The detergent binds to the protein in the dilution stage to form a detergent-protein complex which prevents aggregation of the protein. A binding agent such as cyclodextrin can then be used to strip away the detergent from the protein allowing it to properly refold. Athena’s Detergent Screening Kit provides researchers with 6 common detergents (10mL each) for determining the optimum detergent for a given protein refolding scenario. Individual detergents can also be purchased in quantities.