FUN14 domain containing 1 is a protein that in humans is encoded by the FUNDC1 gene. Model organisms have been used in the study of FUNDC1 function. A conditional knockout mouse line, called Fundc1 was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty two tests were carried out on mutant mice, however no significant abnormalities were observed.