In humans, gamma-glutamyl hydrolase is encoded by the GGH gene. This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. Gamma-glutamyl hydrolase is also known as conjugase, folate conjugase, lysosomal gamma-glutamyl carboxypeptidase, gamma-Glu-X carboxypeptidase, pteroyl-poly-gamma-glutamate hydrolase, carboxypeptidase G, folic acid conjugase, poly (gamma-glutamic acid) endohydrolase, polyglutamate hydrolase, poly (glutamic acid) hydrolase II, pteroylpoly-gamma-glutamyl hydrolase.