This is an info Alert.
  • Home
  • Product
  • Blog
  • Contact

Discover laboratory and life science products for your research. Search our catalog by product name, keyword or catalog number and find the right solution for your laboratory.

Search thousands of research products

Product information & research resources

Support for your product inquiries

Products
All productsSearch products
Resources
ArticlesFAQs
Company
About usContact us
Legal
Terms & conditionsPrivacy policy

© 2026 Gentaur. All rights reserved.
ProductsArticlesContact
0
  1. Home
  2. Products
  3. HuR / ELAVL1 Recombinant Rabbit Monoclonal Antibody [JM96-33]
1/0

HuR / ELAVL1 Recombinant Rabbit Monoclonal Antibody [JM96-33]

Product ID: 8227149


Gentaur Catalog Number

GTR09933633
Select size

100 µL

$726.85
​
Selected
100 µL

$726.85

1

RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA.