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  3. NgR3 Recombinant Rabbit Monoclonal Antibody [JE64-44]
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NgR3 Recombinant Rabbit Monoclonal Antibody [JE64-44]

Product ID: 3209248497526


Gentaur Catalog Number

GTR09936484
Select size

100 µL

$726.85
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Selected
100 µL

$726.85

1

Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.