Microtome cuts embedded tissues into thin slices for applications in histology or pathology. Depending upon the type of specimen and desired thickness it uses blades of diamond, steel or glass for further analysis by light microscopy or transmitted electron microscopy (TEM) . - It have clipper –built case , the user can put blade , wax block , or other consumable one the top of case. It do not need to lubricate and maintain the microtome frequently. The handwheel in the right can be locked in any position, and the handle can be locked in highest - position, it is double safe for changing blade or tissue block. The specimen Orienting system axes X and Y 8°, axis 180°. It adopt the special blade holder , it is more safe and convenient to use the disposable blade - Directly. It also can to longer the user life of disposable blade.